Domaine Billaud-Simon was founded in 1815 by Charles Louis Noel Billaud after his return from the Napoleonic Wars. He planted vines on his family holdings, which were later expanded through the marriage of his relative Jean Billaud to Renée Simon in the 1930s. Located behind high walls near the Serein River, the winery is currently managed by Jean's son, Bernard. It is known as one of the best producers in Chablis. Billaud Simon's 20 hectares in Chablis include vineyards in 4 of the 7 Grand Crus: Blanchots, Les Clos, Les Preuses and Vaudésir, as well as four leading Premier Crus: Fourchaume, Mont de Milieu, Montée de Tonnerre and Vaillons. They also produce AC Chablis from their own fruit in Kimmeridgian (rich in limestone, clay and marine fossils) soils surrounding the 1er and Grand Cru vineyards.

The winery is currently in the process of organic conversion of its vineyards.